Publikationen 2017

  1. Beek van N, Dähnrich C, Johannsen N, Lemcke S, Goletz S, Hübner F, Zenzo di G, Dmochowski M, Drenovska K, Geller S, Horn M, Kowalewski C, Medenica L, Murrell DF, Patsatsi A, Uzun S, Vassileva S, Zillikens D, Schlumberger W, Schmidt E. Prospective studies on the routine use of a novel multivariant enzyme-linked immunosorbent assay for the diagnosis of autoimmune bullous diseases. J Am Acad Dermatol 76(5): 889-894 (2017).
  2. Berzero G, Hacohen Y, Komorowski L, Scharf M, Dehais C, Leclercq D, Fourchotte V, Buecher B, Honnorat J, Graus F, Delattre JY, Psimaras D. Paraneoplastic cerebellar degeneration associated with anti-ITPR1 antibodies. Neurol Neuroimmunol Neuroinflamm 4(2): e326 (2017).
  3. Chen H, Chen S, Lu J, Wang X, Li J, Li L, Fu J, Scheper T, Meyer W, Peng HY, Liu W. Multiparametric detection of antibodies against different EBV antigens to predict risk for nasopharyngeal carcinoma in a high-risk population of China. Cancer Prev Res (Phila) doi: 10.1158/1940-6207.CAPR-17-0035 [Epub] (2017).
  4. Chen J, Zheng Q, Hammers CM, Ellebrecht CT, Mukherjee EM, Tang HY, Lin C, Yuan H, Pan M, Langenhan J, Komorowski L, Siegel DL, Payne AS, Stanley JR. Proteomic analysis of pemphigus autoantibodies indicates a larger, more divers and more dynamic repertoire than determined by B cell genetics. Cell Rep 18(1): 237-247 (2017).
  5. Dammermann W, Polywka S, Dettmann I, Mindorf S, Komorowski L, Wehmeyer M, Schulze Zur Wiesch J, Stöcker W, Lüth S. Autoantibodies against „rods an rings“-related IMPDH2 in hepatitis C genotype 1 and DAA therapy in a „real life“ cohort. Med Microbiol Immunol doi: 10.1007/s00430-017-0516-z [Epub] (2017).
  6. Edmondson DG, Prabhakaran S, Norris SJ, Ullmann AJ, Piesman J, Dolan M, Probst C, Radzimski C, Stöcker W, Komorowski L. Enhanced protective immunogenicity of homodimeric Borrelia burgdorferi Outer Surface Protein C. Clin Vaccine Immunol 24(1)  19 e00306-16 (2017).
  7. Efthymiou G, Dardiotis E, Liaskos C, Marou E, Tsimourtou V, Rigopoulou EI, Scheper T, Daponte A, Meyer W, Sakkas LI, Hadjigeorgiou G, Bogdanos DP. Immune response against Helicobacter pylori-specific antigens differentiates relapsing remitting from secondary progressive multiple sclerosis. Sci Rep 7(1):7929 (2017).
  8. Ernst D, Weiberg D, Baerlecken NT, Schlumberger W, Daehnrich C, Schmidt RE, Bengel FM, Derlin T, Witte T. Anti-MYC-associated zinc finger protein antibodies are associated with inflammatory atherosclerotic lesions on 18F-fluorodeoxyglucose positron emission tomography. Artherosclerosis 259:12-19 (2017).
  9. Finke C, Prüss H, Heine J, Reuter S, Kopp UA, Wegner F, Then Bergh F, Koch S, Jansen O, Münte T, Deuschl G, Ruprecht K, Stöcker W, Wandinger KP, Paul F, Bartsch T. Evalutation of cognitive deficits and structural hippocampal damage in encephalitis with leucine-rich glioma-inactivated 1 antibodies. JAMA Neurol 74(1):50-59 (2017).
  10. Flechsig A, Rose T, Barkhudarova F, Strauss R, Klotsche J, Dähnrich C, Schlumberger W, Enghard P, Burmester GR, Hiepe F, Biesen R. What is the clinical significance of anti-Sm antibodies in systemic lupus erythamtosus? A comparison with anti-dsDNA antibodies and C3. Clin Exp Rheumatol 35(4): 598-606 (2017).
  11. Florey J, Viall A, Streu S, DiMuro V, Riddle A, Kirk J, Perazotti L, Affeldt K, Wagner R, Vaden S, Harris T, Allenspach K. Use of a granulocyte immunofluorescence assay designed for humans for detection of antineutrophil cytoplasmic antibodies in dogs with chronic enteropathies. J Vet Intern Med 31(4): 1062-1066 (2017).
  12. Hahn S, Trendelenburg G, Scharf M, Denno Y, Brakopp S, Teegen B, Probst C, Wandinger KP, Buttmann M, Haarmann A, Szabados F, Vom Dahl M, Kümpfel T, Eichhorn P, Gold H, Paul F, Jarius S, Melzer N, Stöcker W, Komorowski L. Identification of the flotillin-1/2 heterocomplex as a target of autoantibodies in bona fide multiple sclerosis. J Neuroinflammation 14(1): 123 (2017).
  13. Höltje M, Mertens R, Schou MB, Saether SG, Kochova E, Jarius S, Prüss H, Komorowski L, Probst C, Paul F, Bellmann-Strobl J, Gitler D, Benfenati F, Piepgras J, Ahnert-Hilger G, Ruprecht K. Synapsin-antibodies in psychiatric and neurological disorders: prevalence and clinical findings. Brain Behav Immun doi: 10.1016/j.bbi.2017.07.011. [Epub] (2017).
  14. Honorat JA, Komorowski L, Josephs KA, Fechner K, St Loui EK, Hinson SR, Lederer S, Kumar N, Gadoth A, Lennon VA, Pittock SJ, McKeon A. IgLON5 antibody: neurological accompaniments and outcomes in 20 patients. Neurol Neuroimmunol Neuroinflamm 4(5):e385 (2017).
  15. Hormann W, Hahn M, Gerlach S, Hochstrate N, Affeldt K, Giesen J, Fechner K, Damoiseaux J. Performance analysis of automated evaluation of Crithidia luciliae-based indirect immunofluorescence tests in a routine setting – strengths and weaknesses. Clin Chem Lab Med doi 10.1515/cclm-2017-0326 [Epub] (2017).
  16. Hoxha E, Beck LH Jr, Wiech T, Tomas NM, Probst C, Mindorf S, Meyer-Schwesinger C, Zahner G, Stahl PR, Schöpper R, Panzer U, Harendza S, Helmchen U, Salant DJ, Stahl RA. An indirect immunofluorescence method facilitates detection of Thrombonspondin Type 1 Domain-Containing 7A-specific antibodies in membranous nephropathy. J Am Soc Nephrol 28(2): 520-531 (2017).
  17. Jendrek ST, Gotthardt D, Nitzsche T, Widmann L, Korf T, Michaels MA, Weiss KH, Liaskou E, Versterhus M, Karlsen TH, Mindorf S, Schemmer P, Bär F, Teegen B, Schröder T, Ehlers M, Hammers CM, Komorowski L, Lehnert H, Fellermann K, Derer S, Hov JR, Sina C. Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis. Gut 66(1):137-144 (2017).
  18. Lang B, Makuch M, Moloney T, Dettman I, Mindorf S, Probst C, Stoecker W, Buckley C, Newton C, Leite M, Maddison P, Komorowski L, Adcock J, Vincent A, Waters P, Irani S. Intracellular and non-neuronal targets of voltage-gated potassium channel complex antibodies. J Neurol Neurosurg Psychiatry 88(4): 353-361 (2017).
  19. Liaskos C, Marou E, Simopoulou T, Barmakoudi M, Efthymiou G, Scheper T, Meyer W, Bogdanos DP, Sakkas LI. Disease-related autoantibody profile in patients with systemic sclerosis. Autoimmunity doi: 10.1080/08916934.2017.1357699 [Epub] (2017).
  20. Ludwig RJ, Vanhoorelbeke K, Leypoldt F, Kaya Z, Bieber K, McLachlan SM, Komorowski L, Luo J, Cabral-Marques O, Hammers CM, Lindstrom JM, Lamprecht P, Fischer A, Riemekasten G, Tersteeg C, Sondermann P, Rapoport B, Wandinger KP, Probst C, El Beidag A, Schmidt E, Verkman A, Manz RA, Nimmerjahn F. Mechanisms of autoantibody-induced pathology. Front Immunol 8:603 (2017).
  21. Mantere O, Saarela M, Kieseppä T, Raij T, Mäntylä T, Lindgren M, Rikandi E, Stoecker W, Teegen B, Suvisaari J. Anti-neuronal antibodies in patients with early psychosis. Schizophr Res doi: 10.1016/j.schres.2017.04.027. [Epub] (2017).
  22. Marou E, Liaskos C, Efthymiou G, Dardiotis E, Daponte A, Scheper T, Meyer W, Hadjigeorgiou G, Bogdanos DP, Sakkas LI. Increased immunoreactivity against human cytomegalovirus UL83 in systemic sclerosis. Clin Exp Rheumatol PMID: 28240591 [Epub] (2017).
  23. Marou E, Liaskos C, Simopoulou T, Efthymiou G, Dardiotis E, Katsiari C, Scheper T, Meyer W, Hadjigeorgiou G, Bogdanos DP, Sakkas LI. Human cytomegalovirus (HCMV) UL44 and UL57 specific antibody responses in anti-HCMV-positive patients with systemic sclerosis. Clin Rheumatol 36(4): 863-869 (2017).
  24. Mindorf S, Dettmann I, Krueger S, Fuhrmann T, Rentzsch K, Probst C, Komorowski L, Fechner K, van Beek N, Lemcke S, Sardy M, Bienert C, Benoit S, Zillikens D, Pas HH, Jonkmann M, Stoecker W, Schmidt E; International Autoimmune Bullous Diseases Study Group. Routine detection of serum anti-desmocollin autoantibodies is only useful in patients with atypical pemphigus. Exp Dermatol doi: 10.1111/exd.13409. [Epub] (2017).
  25. Munyua P, Corman VM, Bitek A, Osoro E, Meyer B, Müller MA; Lattwein E, Thumbi SM, Murithi R, Widdowson MA, Drosten C, Njenga MK. No serological evidence of Middle East Respiratory Syndrome Coronavirus infection among camel farmers exposed to highly seropositive camel herds: a household linked study, Kenya, 2013. Am J Trop Med Hyg 96(6): 1318-1324 (2017).
  26. Neumann K, Cavalar M, Rody A, Beyer DA. HPV-Infektionen. Diagnostik und Impfung. Tumor Diag u Ther 38: 1-5 (2017).
  27. Popkirov S, Ayzenberg I, Hahn S, Bauer J, Denno Y, Rieckhoff N, Radzimski C, Hans VH, Berg S, Roghmann F, Noldus J, Bien CG, Skodda S, Wellmer J, Stöcker W, Krogias C, Gold R, Schlegel U, Probst C, Komorowski L, Miske R, Kleiter I. Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis. Acta Neuropathol Commun 5(1):40.
  28. Saether SG, Schou M, Stoecker W, Teegen B, Borowski K, Vaaler A, Kondziella D, Reitan SK. Onconeural antibodies in acute psychiatric inpatient care. J Neuropsychiatry Clin Neurosci 29(1): 74-76 (2017).
  29. Satanovskij R, Bader A, Block M, Herbst V, Schlumberger W, Haack T, Nockher WA, Heemann U, Renders L, Schmaderer C, Angermann S, Wen M, Meitinger T, Scherberich J, Steubl D. A new missense mutation in UMOD gene leads to severly reduced serum uromodulin concentrations – a tool for the diagnosis of uromodulin-associated kidney disease. Clin Biochem 50(3): 155-158 (2017).
  30. Scherberich J, Gruber R, Nockher WA, Christensen EI, Schmitt H, Herbst V, Block M, Kaden J, Schlumberger W. Serum uromodulin – a marker of kidney function and renal parenchymal integrity. Nephrol Dial Transplant doi: 10.1093/ndt/gfw422. [Epub] (2017).
  31. Steubl D, Block M, Herbst V, Schlumberger W, Nockher A, Angermann S, Schmaderer C, Heemann U, Renders L, Scherberich J. Serum uromodulin predicts graft failure in renal transplant recipients. Biomarkers 22(2): 171-177 (2017).
  32. Vanderstichele H, Demeyer L, Janelidze S, Coart E, Stoops E, Mauroo K, Herbst V, Francois C, Hansson O. Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1-42)/Aβ(1-40). Alzheimers Res Ther 9(1):40 (2017).
  33. Wang J, Cui Z, Lu J, Probst C, Zhang YM, Wang X, Qu Z, Wang F, Meng LQ, Cheng XY, Liu G, Debiec H, Ronco P, Zhao MH. Circulating antibodies against thrombospondin type-1 domain-containing 7A in Chinese patients with idiopathic membranous nephropathy. Clin J Am Soc Nephrol doi: 10.2215/CJN.01460217 [Epub] (2017).
  34. Willemse E, van Uffelen K, Brix B, Engelborghs S, Vanderstichele H, Teunissen C. How to handle adsorption of cerebospinal fluid amyloid-β (1-42) in laboratory practice? Identifying problematic handlings and resolving the issue by use of the Aβ42/Aβ40 ratio. Alzheimers Dement 13(8): 885-892 (2017).
  1. Chunder R, Linington C, Graus F, Sabater L, Stöcker W, Komorowski L, Probst C. Recombinant cell-based indirect immunofluorescence assay for the detection of IgM anti-HNK-1 paraproteins in polyneuropathy. American Academy of Neurology 69. Annual Meeting, Boston, USA (2017).
  2. Hahn S, Trendelenburg G, Scharf M, Denno Y, Brakopp S, Teegen B, Probst C, Wandinger KP, Buttmann M, Szabados F, Dahl vom M, Kümpfel T, Eichhorn P, Gold HJ, Jarius S, Melzer N, Stöcker W, Komorowski L. Identification of the flotillin-1/2 heretocomplx as a target of autoantibodies in multiple sclerosis. American Academy of Neurology 69. Annual Meeting, Boston, USA (2017).
  3. Herbst V, Brix B, Block M. New automated chemiluminescence immunoassay for CSF beta-amyloid determination. 11. International Conference on Alzheimer’s and Parkinson’s Disease, Wien, Österreich (2017).
  4. Herbst V, Brix B, Vanderstichele HM. A novel colorimetric ELISA for quantification of tau, phosphorylated at threonine 181, in cerebrospinal fluid. Alzheimer`s Association International Conference 2017, London, England (2017).
  5. Kade S, Strippel C, Teegen B, Miske R, Scharf M, Denno Y, Probst C, Radzimski C, Stöcker W, Melzer N, Komorowski L. Identification of the CNTN1/CASPR complex as the target of autoantibodies in a patient with chronic inflammatory demyelinating polyneuropathy. American Academy of Neurology 69. Annual Meeting, Boston, USA (2017).
  6. Oesterreich B, Klemens O, Fraune J, Streit A, Warnecke JM, Steinhagen K. Novel ELISA using antigens from Strongyloides papillosus instead of S. ratti exhibit increased serological specificity. 27. ECCMID, Wien, Österreich (2017).
  7. Scharf M, Miske R, Kade S, Hahn S, Begemann N, Denno Y, Probst C, Teegen B, Borowski K, Stöcker W, Komorowski L. The role of mass spectrometry in the identification of autoantibodies as targets in neurological autoimmune diseases. 50. Jahrestagung der Deutschen Gesellschaft für Massenspektrometrie, Kiel, Deutschland (2017).
  8. Scherberich J, Delgado GE, Kleber M, Scharnagl H, Krämer BK, Herbst V, Block M, Christensen EI, Nockher W, Schlumberger W, März W. Serum uromodulin: an early diagnostic and prognostic tissue-specific marker of kidney injury. Symposium Biomarkers of the Cardiorenal axis, DACH-Gesellschaft, Mannheim, Deutschland (2017).
  9. Steinhagen K, Lattwein E, Fraune J, Schlumberger W, Warnecke J. Absence of specific IgM in week six post symptom onset in a patient with confirmed Zika virus infection. 1. International Conference on Zika Virus, Washington, USA (2017). 
  10. Steinhagen K, Sendscheid O, Klemens JM, Fraune J, Schlumberger W. Combined detection of specific IgG and IgM antibodies for a reliable screening for West-Nile virus infections. 33. Clinical Virology Symposium of the American Society for Microbiology, Savannah, USA (2017).
  11. Vanderstichele H, Chassaing E, Demeyer L, Pannee J, Herbst V, Bodnar-Wachtel M, Stoops E, Hansson O, Blennow K. Differences in analytical selectivity of β-amyloid (1-42) immunoassays explains discordant results in study comparisons. Alzheimer's Association International Conference 2017, London, England (2017).
  12. Wilhelm N, Klemens JM, Steinhagen K, Schlumberger W. New diagnostic markers for differentiation of acute and convalescent human cytomegalovirus infections. Eingereicht als Posterpräsentation bei der 27. ECCMID, Wien, Österreich (2017).
  1. Brix B, Vanderstichele HM, Janelidze S, Demeyer L, Coart E, Stoops E, Hansson O. The CSF Aβ(1-42)/Aβ(1-40) ratio improves the clinical utility of Aβ(1-42) by its impact at analytical and clinical level. Alzheimer`s Association International Conference 2017, London, England (2017).
  2. Gille B, Schaeverbeke J, Vanderstichele HM, Adamczuk K, Demeyer L, Francois C, Herbst V, Brix B, Tournoy J, Vandenberghe R, Poesen K. Synaptic markers in liquor inversely correlate with grey matter volume in cognitively healthy individuals. Alzheimer`s Association International Conference 2017, London, England (2017).
  3. Mindorf S, Dettmann IM, Krüger S, Rentzsch K, Fuhrmann T, Probst C, Komorowski L, Fechner K, Beek van N, Lemcke S, Sárdy M, Bengert C, Benoit S, Hashimoto T, Zillikens D, Pas HH, Jonkman M, Stöcker W, Schmidt E, International Autoimmune Bullous Disease Study Group. Die diagnostische Relevanz von Anti-Desmocollin Antikörpern bei Pemphiguserkrankungen. 49. DDG-Tagung, Berlin, Deutschland (2017).
  4. Miske R, Scharf M, Borchers C, Denno Y, Teegen B, Rochow N, Probst C, Stöcker W, Kermer P, Komorowski L. Identification of RGS8 as an autoantibody target in paraneoplastic cerebellar syndrome. XXVI AINI Congress/16. ESNI Course, Venedig, Italien (2017).
  5. Steinhagen K, Wilhelm N, Schmidt-CHanasit J, Emmerich P, Huzly D, Lattwein D, Fraune J, Schlumberger W, Warnecke J. Anti-Zika virus IgA may indicate an acute infection in anti-Zika virus IgM-negative patients. 1. International Conference on Zika Virus, Washington, USA (2017).
  6. Stoecker W. Techniques in autoimmune diagnostics. Avancées majeures en auto-immunité, Groupe d’Ètude de l’Auto-Immunité Marocain. Casablanca, Marokko (2017).
  7. Stoecker W. Antibodies against neuronal antigens. Avancées majeures en auto-immunité, Groupe d’Ètude de l’Auto-Immunité Marocain. Casablanca, Marokko (2017).
  8. Verbeek M, Neville D, van Gerresheim E, Vanderstichele HM, Brix B, Steiger A, Dresler M. Association between nocturnal amyloid beta fluctuations and sleep. Alzheimer`s Association International Conference 2017, London, England (2017).
  1. Pannhoff H, Feirer C. Calibration standrad for a device for image-based representation of biological material. Japanische Patentanmeldung 2017-502280 (angemeldet 2014).
  2. Stöcker W. Verbesserte Vorrichtung und Verfahren für Reaktionen zwischen einer festen und einer flüssigen Phase.  Japanische Patenanmeldung 2017-500585A (angemeldet 2014).