Insect venoms

Clinical significance

Localised pain, swelling, itching and redness are normal reactions to an insect bite. However, insect bites can also cause allergic reactions that can manifest minutes or even hours after the bite.

Symptoms range from skin reactions such as hives, swelling, itching and redness (not necessarily limited to the site of the bite) to severe systemic reactions, presenting as swelling of the throat and tongue, dyspnoea, nausea, intestinal and stomach complaints, diarrhoea, neurological complaints including confusion, vertigo, disturbed gait, rapid heartbeat and low blood pressure. In the worst case, the reaction may lead to life-threatening anaphylactic shock. It is estimated that 1% to 7% of the population suffer from insect venom allergy.

Diagnostics

For clarification of insect venom allergies, differential diagnostics are recommended to identify the exact allergy-inducing species. EUROIMMUN offers different insect venoms profiles (EUROLINE) that contribute to the identification of sensitisations to the most common insect venoms. In addition to natural insect venom extracts, the profiles also include recombinant species-specific allergen components (defined partial allergen diagnostics (DPA-Dx)) for simultaneous in vitro determination of human IgE antibodies.

In addition, the total IgE concentration in serum or plasma can be determined using the Total IgE ELISA.

Files

DPA-Dx Insect Venoms - Modern diagnostics for the differentiation of insect venom allergies

IDS Allergy - Portfolio

IDS Allergy - Total IgE

IDS Allergy - Your partner for modern allergy diagnostics

EUROAssay products are only available in Germany.

Techniques

Method
Parameter
Substrate
ChLIA
IDS Positive Specific IgE Control (F003) Cod 1
2 x 1.2mL Control 1
ChLIA
IDS Positive Specific IgE Control (G006) Timothy Grass 1
2 x 1.2mL Control 1
ChLIA
IDS Negative Specific IgE Control (F003/G006) Cod/Timothy Grass 1
2 x 1.2mL Control 1
ChLIA
IDS Total IgE Control Set 1
1 x 1.2mL Control 1/2/3
ELISA
total IgE
antigen-coated
microplate wells
ChLIA
IDS Total / Specific IgE Reagent Kit 1
magnetic particles
EUROASSAY
DPA-Dx insect venoms 3
(i1, i3, i75, i208, i213, i216, i209, i211, CCD)
EUROASSAY strip
with allergens
EUROLINE
DPA-Dx insect venoms 3
(i1, i3, i75, i208, i213, i216, i209, i211, CCD)
membrane strip with allergens
(EUROLINE)
EUROLINE
DPA-Dx insect venoms "Southern Europe 1"
(i1, i3, i75, i77, i208, i213, i216, i210, i209, i220, i211, CCD)
membrane strip with allergens
(EUROLINE)
ChLIA
IDS Specific IgE (I001) Honey bee 1
allergen
ChLIA
IDS Specific IgE (I003) Wasp 1
allergen
1Product manufactured by third party. Please contact your local EUROIMMUN representative for more information.
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